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New Phase 3 Paid COPD Clinical Trial Now Enrolling at Avail Clinical Research Near Orlando, Florida; Now Enrolling Participants Age 18-75


DeLand, Florida (PRWEB) November 12, 2012

According to the World Health Organization, COPD was the fifth leading cause of death worldwide in 2002 and is estimated to be the third leading cause by 2030 [WHO, 2010].

Are you a current or ex-smoker are suffering from a new or increased shortness of breath, cough, or congestion? If have COPD, Bronchitis, Emphysema or suffer from these symptoms this trial may fit for you.

Chronic obstructive pulmonary disease (COPD) has been defined as a preventable and treatable disease with some significant extra-pulmonary effects that may contribute to the severity in individual patients. The pulmonary component of COPD is characterized by airflow limitation that is not fully reversible, which is usually progressive and associated with an abnormal inflammatory response of the lung to noxious particles or gases. COPD is a major cause of poor health, resulting in millions of deaths annually worldwide [GOLD, 2010] and contributing significantly to health care costs and morbidity [Chapman, 2006; Lopez, 2006].

**Avail Clinical Research is now enrolling for this Paid COPD Clinical Trial. To get started, visit http://ECigBrandStarterKit.com/go/free-trial or call us directly at (386) 310-1334.

STUDY DESIGN

This will be a Phase IIIb multi-center, randomized, double-blind, double-dummy, 12-week parallel group study evaluating the effects of once daily in the morning treatment of a new drug versus an existing one, twice daily on lung function in COPD subjects.

Subjects will visit the clinic a minimum of 5 times over a 14-week period. Visit 5 will be an overnight stay in the clinic. A safety Follow-up Visit 6, 7 days post the last treatment study day will occur as a telephone contact. Subjects will be prescribed appropriate COPD therapy at the end of Treatment Visit 5 if required.

There are no plans to provide the study drug for compassionate use following study completion. The target enrolment across approximately 85 study centers is approximately 800 randomized subjects, to achieve approximately 680 who complete the 12-week treatment period. The total duration of subject participation will be approximately 15 weeks.

INCLUSION CRITERIA

Specific information regarding warnings, precautions, contraindications, adverse events, and other pertinent information on the investigational product or other study deviations from inclusion criteria are not allowed because they can potentially jeopardize the scientific integrity of the study, regulatory acceptability or subject safety. Therefore, adherence to the criteria as specified in the protocol is essential.

Subjects eligible for enrolment in the study must meet all of the following criteria:

1. Informed consent: Subjects must give their signed and dated written informed consent to participate.

2. Gender: Males or females. Female subjects must be post-menopausal or using a highly effective method for avoidance of pregnancy. The decision to include or exclude women of childbearing potential may be made at the discretion of the investigator in accordance with local practice in relation to adequate contraception.

3. Age: 40 years of age at Screening (Visit 1)

4. COPD diagnosis: Subjects with a clinical history of COPD in accordance with the following definition by the American Thoracic Society/European Respiratory Society [Celli, 2004]: COPD is a preventable and treatable disease characterized by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and is associated with an abnormal inflammatory response of the lungs to noxious particles or gases, primarily caused by cigarette smoking. Although COPD affects the lungs, it also produces significant systemic consequences.

5. Severity of Disease:


Subject with a measured post-albuterol (salbutamol) FEV1/FVC ratio of 0.70 at Screening (Visit 1) [Pelligrino, 2005]

Subjects with a measured post-albuterol (salbutamol) FEV1 70% of predicted normal values calculated (via centralized vendor equipment) using NHANES III reference equations [Hankinson, 1999] at Screening (Visit 1).

Post-bronchodilator spirometry will be performed approximately 10-15 minutes after the subject has self-administered 4 inhalations (i.e., total 400mcg) of albuterol (salbutamol) via an MDI with a valved-holding chamber. The study-provided central spirometry equipment will calculate the FEV1/FVC ratio and FEV1 percent predicted values.

6. Tobacco use: Subjects with a current or prior history of 10 pack-years of cigarette smoking at Screening (Visit 1). Former smokers are defined as those who have stopped smoking for at least 6 months prior to Visit 1. Note: Pipe and/or cigar use cannot be used to calculate pack-year history. Number of pack years = (number of cigarettes per day/20) x number of years smoked.

**Avail Clinical Research is now enrolling for this Paid COPD Clinical Trial. Learn more about COPD Awareness Month, or to get started visit http://ECigBrandStarterKit.com/go/free-trial or call us directly at (386) 310-1334.







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Q&A: Is there really any way to get an electronic cigarette free trial?

Question by Jason P: Is there really any way to get an electronic cigarette free trial?
I see lots of site offering a “free” trial but when I order them, it says I get 5 free cartridges or something stupid like that. PLEASE HELP, I want to quit smoking!

Best answer:

Answer by Jason P
First of all, KUDOS for wanting to quit smoking! I went through the same struggle for a long time to quit. I smoked for 9 years, and when I heard about electronic cigarettes I was compelled to try them, only because nothing else worked. I had tried cold turkey, I had tried the patch, and gum. Then I realized that it was going to be way harder than I expected.

While using search engines to find a trial (much like yourself) I found one that offers a good trial, where I paid only shipping. http://ECigBrandStarterKit.com/go/free-trial is where its located. I think you were thinking about the njoy or ritesmoke free trials, that aren’t really free trials. I tried both of them, and they want you to pay $ 70 or something stupid.

Now, I still smoke the e-cigs. They handle my craving, taste similar to real cigarettes, and are alot cheaper in the end. The nicotine delivery feels the same, and you blow out water vapor that looks like smoke.

Anyways, hope this helps.

http://ECigBrandStarterKit.com/go/free-trial

Know better? Leave your own answer in the comments!

Electronic Cigarette Free Trial: 40 Year Study Reveals Cutting Down On Smokes …

Electronic Cigarette Free Trial: 40 Year Study Reveals Cutting Down On Smokes
Nicotine addiction is one of the major challenges smokers face when trying to quit smoking. In its support, http://ECigBrandStarterKit.com/go/free-trial is distributing free electronic cigarette trial kits under its try before buy campaign. Whether you want to …
Read more on Midland Daily News

Get A Free Electronic Cigarette Trial Kit & Quit Smoking Before 2013. Don't
Nicotine addiction is one of the major challenges smokers face when trying to quit smoking. In its support, http://ECigBrandStarterKit.com/go/free-trial is distributing free electronic cigarette starter kits under its try before buy campaign. You don't need to …
Read more on Midland Daily News

Free Electronic Cigarette Trial: Smoking Claims 440,000 Lives In US Annually, Doctors Suggest Use Of E Cig As Beneficial For Health


(PRWEB) November 23, 2012

Sive Ancheta, a 43 year old e cigarette user says, I wasn’t a heavy smoker, but my significant other brought home a disposable electronic cigarette and I gave that a try. I decided right then and there that I was going to use the e cigarettes from now on because the flavor was a lot better than a cigarette, and the vapor is definitely not as heavy as cigarette smoke. I actually got my sense of taste back to 100%. She claims she is far healthier and better off now thanks to smokeless cigarettes.

Click Here For A Free E Cigarette Trial Kit

According to a new survey, smoking is also considered the cause of death of over 440,000 people in USA and over 100,000 in UK.

Smoking is responsible for many diseases including lung and many other forms of cancer. Most of the diseases associated with smoking are long-term chronic, and heart diseases. Despite of so many diseases associated with tobacco cigarettes, people are still struggling to quit smoking. A recent survey reveals that over 700, 000 people in US alone are using electric cigarettes in order to quit smoking. The ecigarettes are safer alternatives that many smokers who are heavily addicted and cannot quit smoking switch to. In US, almost 20% of death out of the 2.4 million deaths annually results from smoking.

All smokeless cigarette starter kits have a lifetime guarantee and contain:

Smokeless Cigarettes Free Trial – Try Electronic Cigarette!

ElectronicCigaretteHub.org – Try smokeless cigarettes for free today! Smokeless cigarettes work just like a nicotine patch and nicotine gum which give user their nicotine fix. Updated electronic cigarette http ecigarette news. Additional electronic cigarette videos: www.youtube.com But, there’s more to smoking than just getting the nicotine fix. There is a certain fixation about smoking: The way you hold the cigarette, the puffing and seeing the smoke coming out of your mouth. The e-cigarette offers the same smoking experience. You hold it like a cigarette, you puff it like you do a cigarette, and you’ll see ‘smoke’ coming out of your mouth like a cigarette. Except that it’s not a smoke, it’s vapor. Some people will be able to quit smoking only a week after switching to the smokeless cigarettes! Here’s what usually happens: Once people get used to the e-cigarette, they get uncomfortable with the smell of a regular tobacco cigarette smoke. So, they will stop smoking the regular cigarette for good. Following that, they switched to the low-nicotine cartridge and eventually they will stop needing the nicotine fix. Smokers know smoking is bad for health. But, it’s not the nicotine which makes smoking harmful. Nicotine is like caffeine to a coffee drinker: It’s addictive. The e-cigarette is an alternative for those who need the nicotine fix with minimal damage to their body and those around them. The battery-powered, non-flammable device provides a smoking experience without
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Q510 Trial E cig Starter Kit Review

A great starter kit for those who want to try an e cig without a huge investment. Plus even when the batt dies you still have a decent atty and a USB charger for an auto 510 batt for .96

Direct E Cig : Watch Before You Buy Electronic Cigarettes Direct (Trial Pack)

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